Diltiazem 2% Ointment Compounding by Noor Chemist
₨ 450
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Diltiazem 2% + lidocaine anorectal ointment
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Chronic fissure treatment
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Muscle relaxant + anesthetic
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AJK-licensed compounding
Size and packaging guidelines
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| Specification | Chair | Armchair | Sofas |
| Height | 37" | 42" | 42" |
| Width | 26.5" | 32.5" | 142" |
| Depth | 19.5" | 22.5" | 24.5" |
| Assembly Required | No | No | Yes |
| Packaging Type | Box | Box | Box |
| Package Weight | 55 lbs. | 64 lbs. | 180 lbs. |
| Packaging Dimensions | 27" x 26" x 39" | 45" x 35" x 24" | 46" x 142" x 25" |
Description
This specialized compounded formulation licensed by the Government of AJ&K combines diltiazem (calcium channel blocker) with lidocaine for chronic anal fissure management. The ointment reduces internal sphincter hypertonia by 58% while providing immediate pain relief, promoting healing in >90% of acute fissures within 4 weeks. Pharmacopeia-grade preparation ensures optimal mucosal penetration without systemic absorption.
Ingredients & Mechanisms
| Component | Concentration | Role & Clinical Action |
|---|---|---|
| Diltiazem HCl | 2% | Smooth muscle relaxant: Inhibits calcium influx in sphincter muscles |
| Lidocaine HCl | 3% | Anesthetic: Blocks Na⁺ channels (onset: 2-4 mins) |
| Base | Water-washable | Enhances mucosal adhesion; non-greasy |
Primary Indications
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Chronic anal fissures (>6 weeks)
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Post-hemorrhoidectomy spasm
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Anodermal hypertonia
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Pre-defecation pain management
Therapeutic Advantages
✅ Dual-Action: Muscle relaxation + immediate analgesia
✅ Superior Efficacy: 92% healing rate vs. 70% with GTN ointments
✅ No Systemic Effects: Plasma levels undetectable (<5 ng/mL)
✅ Non-Headache Inducing: Avoids nitrate-related side effects
✅ Customizable: Strength adjustable (1-4% diltiazem)
Application Protocol
| Condition | Method | Frequency | Duration |
|---|---|---|---|
| Acute Fissure | Apply pea-sized amount intra-anally | BID | 6-8 weeks |
| Post-Op Care | Apply to surgical site | TID | 2 weeks |
| Painful Defecation | Apply 5 mins pre-bowel movement | PRN | As needed |
Precautions
⚠️ Avoid if: Hypotension, heart block, or lidocaine allergy
⚠️ Discontinue if perianal rash develops
⚠️ Pregnancy Category C (limited studies)
✖️ Not for children <18 years
Disclaimer
All compounded preparations by Noor Chemist are freshly prepared upon receipt of your prescription or order to ensure maximum potency and therapeutic efficacy. Due to the meticulous quality control processes required for extemporaneous compounding, some formulations may experience a 1-day preparation delay to achieve optimal stability and performance. Product images depicting packaging and labeling are for illustrative reference only; actual containers, labels, and auxiliary materials may vary based on batch-specific pharmaceutical standards.
These formulations are designed for short-term use (typically 30-90 days), as extemporaneous compounds lack industrial preservatives. For specific storage instructions and shelf-life details pertaining to your formulation, please contact our pharmacists via our Contact Us portal.
Important Safety Notice: Skin sensitivity to active or inert ingredients may occur even with physician-recommended formulations. We strongly advise performing a patch test before full application: Apply a pea-sized amount to clean inner forearm skin, wait 24 hours, and discontinue use if redness, itching, or swelling develops. Individual reactions to ingredients like salicylic acid, essential oils, or penetration enhancers may vary. Consult your healthcare provider if you have known sensitivities.
All orders are securely shipped nationwide and internationally via our trusted courier partners, Leopards Courier or TCS Courier. Products are carefully packed to ensure safe transit, and we actively track every shipment until delivery. Domestic shipping charges are Rs. 250 for Leopards Courier and Rs. 330 for TCS Courier. For international orders, please contact our team before placing your order, as shipping rates vary by destination. We deliver globally with the same commitment to careful handling and real-time tracking.

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