Diabetic Foot Gel Compounding by Noor Chemist

Description

This sterile-compounded hydrogel licensed by the Government of AJ&K (License No. 501/DHO/2020) combines regenerative hyaluronic acid with sustained-release iodine for diabetic foot ulcer (DFU) management. The mucoadhesive matrix maintains optimal moisture balance (90% relative humidity) while delivering broad-spectrum antimicrobial action against biofilm-forming pathogens. Ideal for Wagner Grade 1-2 ulcers, it promotes angiogenesis and granulation tissue formation without cytotoxic effects on fibroblasts.

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Ingredients & Clinical Mechanisms

Note: Iodine complexed with povidone reduces cytotoxicity while maintaining efficacy.

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Primary Indications

• Neuropathic Ulcers: Promotes granulation in pressure points (metatarsal heads/heels)

• Post-Debridement Care: Fills irregular wound beds with HA scaffold

• Prophylaxis: Daily application to pre-ulcerative lesions (calluses/fissures)

• Colonized Wounds: Reduces bioburden in critically colonized DFUs

• Post-Amputation Care: Protects residual limb incision sites

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Key Advantages

✅ Biofilm Penetration: Iodine complex penetrates EPS matrix 3× better than silver dressings
✅ Regenerative Environment: HA increases fibroblast migration by 78% vs. saline
✅ Moisture Control: Absorbs 300% exudate without maceration
✅ Non-Cytotoxic: Preserves keratinocyte viability (>95% in vitro)
✅ Sterile Manufacturing: Compounded in ISO Class 5 laminar flow hood

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Application Protocol

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Precautions

⚠️ Contraindications: Thyroid disorders, iodine allergy, deep sinus tracts
⚠️ Thyroid Monitoring: Check TSH if used on >10% BSA for >4 weeks
⚠️ Staining: Temporarily stains skin/clothing (washes with soap)
⚠️ Interactions: Inactivated by blood/pus (cleanse with saline first)
✖️ Not for Wagner Grade 3+ ulcers (exposed bone/tendon)

Disclaimer

All compounded preparations by Noor Chemist are freshly prepared upon receipt of your prescription or order to ensure maximum potency and therapeutic efficacy. Due to the meticulous quality control processes required for extemporaneous compounding, some formulations may experience a 1-day preparation delay to achieve optimal stability and performance. Product images depicting packaging and labeling are for illustrative reference only; actual containers, labels, and auxiliary materials may vary based on batch-specific pharmaceutical standards.

These formulations are designed for short-term use (typically 30-90 days), as extemporaneous compounds lack industrial preservatives. For specific storage instructions and shelf-life details pertaining to your formulation, please contact our pharmacists via our Contact Us portal.

Important Safety Notice: Skin sensitivity to active or inert ingredients may occur even with physician-recommended formulations. We strongly advise performing a patch test before full application: Apply a pea-sized amount to clean inner forearm skin, wait 24 hours, and discontinue use if redness, itching, or swelling develops. Individual reactions to ingredients like salicylic acid, essential oils, or penetration enhancers may vary. Consult your healthcare provider if you have known sensitivities.