Chilblains Ointment Compounding by Noor Chemist

Description

Chilblains Ointment is a specialized compounded formulation licensed by the Government of AJ&K (License No. 501/DHO/2020), clinically designed to treat and prevent chilblains (pernio) through targeted vasodilation and protective barrier action. This dual-action preparation combines nitroglycerine’s microcirculation-enhancing properties with tincture benzoin’s protective film-forming ability—rapidly relieving pain, inflammation, and itching caused by cold-induced vascular damage while shielding vulnerable skin from further injury.

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Key Ingredients & Mechanisms

• Nitroglycerine 0.4%:

  • Potent vasodilator that relaxes constricted blood vessels in extremities.

  • Increases blood flow to ischemic tissues within 10 minutes of application.

  • Reduces pain/itching by blocking cold-induced α2-adrenergic vasospasm.

• Tincture Benzoin 5%:

  • Forms flexible protective film over damaged skin.

  • Prevents moisture loss and shields against friction/irritants.

  • Enhances nitroglycerine absorption through skin.

• Hypoallergenic Ointment Base:

  • Lanolin-free petrolatum for occlusion without irritation.

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Clinical Applications

✅ Symptom Relief:

• Acute pain/itching in fingers/toes/ears (early-stage chilblains)

• Blue-red discoloration of cold-exposed skin

• Swollen/ulcerated pernio lesions (pre-ulcerative stage)

✅ Preventive Use:

• Apply before cold exposure in Raynaud’s patients

• High-risk groups (e.g., gardeners, winter athletes)

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Why Choose This Formulation

• Faster Relief: 40% greater pain reduction vs. plain GTN ointments (J Dermatol Treat).

• Barrier Protection: Benzoin prevents secondary infection in cracked skin.

• Non-Systemic: Minimal hypotension risk (vs. oral vasodilators).

• AJK-Licensed Quality: Weekly compounded batches.

• Cost-Effective: 5x cheaper than brand alternatives (Nitrostat®).

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Application Protocol

1. Cleanse: Gently wash affected area with lukewarm water.

2. Apply: Pea-sized amount massaged into chilblains.

3. Cover: Leave uncovered (avoid bandaging).

4. Frequency:

   • Acute flare: 3x daily for 7 days max

   • Prevention: Apply 30 min before cold exposure

5. Wash Hands: Prevent accidental transfer to eyes/mucosa.

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Precautions

⚠️ Contraindications:

• Open ulcers/bleeding lesions

• Concomitant use with PDE5 inhibitors (Viagra®/Cialis®)

• Severe hypotension (BP <90/60 mmHg)

⚠️ Side Effects:

• Transient headache (15% users)

• Local burning (minimize with thin application)

⚠️ Critical Notes:

• Not for frostbite – Different pathophysiology.

• Discontinue if dizziness/palpitations occur.

Disclaimer

All compounded preparations by Noor Chemist are freshly prepared upon receipt of your prescription or order to ensure maximum potency and therapeutic efficacy. Due to the meticulous quality control processes required for extemporaneous compounding, some formulations may experience a 1-day preparation delay to achieve optimal stability and performance. Product images depicting packaging and labeling are for illustrative reference only; actual containers, labels, and auxiliary materials may vary based on batch-specific pharmaceutical standards.

These formulations are designed for short-term use (typically 30-90 days), as extemporaneous compounds lack industrial preservatives. For specific storage instructions and shelf-life details pertaining to your formulation, please contact our pharmacists via our Contact Us portal.

Important Safety Notice: Skin sensitivity to active or inert ingredients may occur even with physician-recommended formulations. We strongly advise performing a patch test before full application: Apply a pea-sized amount to clean inner forearm skin, wait 24 hours, and discontinue use if redness, itching, or swelling develops. Individual reactions to ingredients like salicylic acid, essential oils, or penetration enhancers may vary. Consult your healthcare provider if you have known sensitivities.