Cosmetics
Dermatology
Pain Relief
Protection
Theraputics
Wound Care
Compound Ointment Compounding by Noor Chemist
₨ 600
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Clobetasol 30% Diluted + SA 5% + urea 10% + benzoic acid 3%
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Antifungal/keratolytic/steroid triple-action
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Vitamin E stabilized
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For hyperkeratotic fungal/psoriatic lesions
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AJK-licensed compounding
Description
This triple-action compounded formulation licensed by the Government of AJ&K (License No. 501/DHO/2020) combines antifungal, keratolytic, and anti-inflammatory agents for resistant hyperkeratotic dermatoses. Pharmacopeia-grade actives penetrate thickened plaques via urea-salicylic acid synergy while clobetasol suppresses inflammation. Vitamin E prevents oxidation, enhancing stability in tropical climates. Ideal for moccasin-type tinea pedis, hypertrophic psoriasis, and palmoplantar hyperkeratosis unresponsive to monotherapies.
Ingredients & Clinical Rationale
| Component | Concentration | Mechanism & Purpose |
|---|---|---|
| Salicylic Acid | 5% | Keratolytic: Disrupts corneocyte bonds via desmosomal hydrolysis (pH 3.5–4.0) |
| Urea | 10% | Humectant keratolytic: Hydrates + dissolves keratin (NMF enhancement) |
| Benzoic Acid | 3% | Antifungal: Disrupts fungal cell membranes (synergistic with SA) |
| Clobetasol Propionate | 0.05% | Ultra-potent steroid: Inhibits IL-2/COX-2 (98% vasoconstriction) |
| Lactic Acid | 1% | Alpha-hydroxy acid: Reduces stratum corneum adhesion (pH balancer) |
| Vitamin E (d-α-tocopheryl) | 0.5% | Antioxidant: Prevents oxidation of unsaturated acids |
| Base | 80.45% | Penetration-enhanced ointment (PG-free) |
Primary Indications
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Fungal Hyperkeratosis: Dual antifungal action against T. rubrum + keratolytic debridement
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Psoriatic Plaques: SA/urea/clobetasol penetrates >2mm into plaques (vs. 0.8mm in commercial creams)
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Lichenified Eczema: Steroid delivery through fissured barriers
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Plantar Callus: Urea-SA softens hyperkeratosis in 72h
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Reactive Dermatitis: Post-procedure inflammation control
Why Choose This Formulation
✅ Synergistic Penetration: Urea 10% increases SA absorption 3-fold vs. standalone
✅ Stability Optimized: Vitamin E reduces acid degradation (shelf life +18 months)
✅ Concentration Accuracy: HPLC-verified active potency (±2% margin)
✅ Non-Occlusive Base: Permits sweat evaporation (critical for foot/skin folds)
✅ AJK Compliance: Quarterly sterility testing (BP Appendix XVI)
Application Protocol
| Condition | Method | Max Duration |
|---|---|---|
| Plantar Psoriasis | Apply under occlusion (plastic wrap) | 2 weeks |
| Moccasin Tinea | Thin layer AM/PM after foot soak | 4 weeks |
| Hand Hyperkeratosis | Nightly + cotton gloves | 3 weeks |
| CRITICAL: Do not exceed 50g/week or 25% BSA due to clobetasol potency. |
Precautions
⚠️ Contraindications: Rosacea, perioral dermatitis, ulcerated skin
⚠️ Systemic Risks: Hypothalamic-pituitary axis suppression with prolonged use
⚠️ Interactions: Incompatible with sulfur/reducing agents
⚠️ Pregnancy: Category C (avoid on large areas)
✖️ Not for children under 12
Disclaimer
All compounded preparations by Noor Chemist are freshly prepared upon receipt of your prescription or order to ensure maximum potency and therapeutic efficacy. Due to the meticulous quality control processes required for extemporaneous compounding, some formulations may experience a 1-day preparation delay to achieve optimal stability and performance. Product images depicting packaging and labeling are for illustrative reference only; actual containers, labels, and auxiliary materials may vary based on batch-specific pharmaceutical standards.
These formulations are designed for short-term use (typically 30-90 days), as extemporaneous compounds lack industrial preservatives. For specific storage instructions and shelf-life details pertaining to your formulation, please contact our pharmacists via our Contact Us portal.
Important Safety Notice: Skin sensitivity to active or inert ingredients may occur even with physician-recommended formulations. We strongly advise performing a patch test before full application: Apply a pea-sized amount to clean inner forearm skin, wait 24 hours, and discontinue use if redness, itching, or swelling develops. Individual reactions to ingredients like salicylic acid, essential oils, or penetration enhancers may vary. Consult your healthcare provider if you have known sensitivities.
All orders are securely shipped nationwide and internationally via our trusted courier partners, Leopards Courier or TCS Courier. Products are carefully packed to ensure safe transit, and we actively track every shipment until delivery. Domestic shipping charges are Rs. 250 for Leopards Courier and Rs. 330 for TCS Courier. For international orders, please contact our team before placing your order, as shipping rates vary by destination. We deliver globally with the same commitment to careful handling and real-time tracking.
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