Diltiazem 2% Ointment Compounding by Noor Chemist

₨ 450

Diltiazem 2% + lidocaine anorectal ointment
Chronic fissure treatment
Muscle relaxant + anesthetic
AJK-licensed compounding

Size and packaging guidelines

Fermentum scelerisque hendrerit parturient nullam enim lobortis litora parturient dictumst.

Potenti a quisque tincidunt venenatis adipiscing parturient fermentum nisl tincidunt amentu.

Scelerisque conubia lobortis a condimentum ad eleifend dui integer maecenas habitant nostra.

Specification	Chair	Armchair	Sofas
Height	37"	42"	42"
Width	26.5"	32.5"	142"
Depth	19.5"	22.5"	24.5"
Assembly Required	No	No	Yes
Packaging Type	Box	Box	Box
Package Weight	55 lbs.	64 lbs.	180 lbs.
Packaging Dimensions	27" x 26" x 39"	45" x 35" x 24"	46" x 142" x 25"

Description

This specialized compounded formulation licensed by the Government of AJ&K combines diltiazem (calcium channel blocker) with lidocaine for chronic anal fissure management. The ointment reduces internal sphincter hypertonia by 58% while providing immediate pain relief, promoting healing in >90% of acute fissures within 4 weeks. Pharmacopeia-grade preparation ensures optimal mucosal penetration without systemic absorption.

Ingredients & Mechanisms

Component	Concentration	Role & Clinical Action
Diltiazem HCl	2%	Smooth muscle relaxant: Inhibits calcium influx in sphincter muscles
Lidocaine HCl	3%	Anesthetic: Blocks Na⁺ channels (onset: 2-4 mins)
Base	Water-washable	Enhances mucosal adhesion; non-greasy

Primary Indications

Chronic anal fissures (>6 weeks)
Post-hemorrhoidectomy spasm
Anodermal hypertonia
Pre-defecation pain management

Therapeutic Advantages

✅ Dual-Action: Muscle relaxation + immediate analgesia
✅ Superior Efficacy: 92% healing rate vs. 70% with GTN ointments
✅ No Systemic Effects: Plasma levels undetectable (<5 ng/mL)
✅ Non-Headache Inducing: Avoids nitrate-related side effects
✅ Customizable: Strength adjustable (1-4% diltiazem)

Application Protocol

Condition	Method	Frequency	Duration
Acute Fissure	Apply pea-sized amount intra-anally	BID	6-8 weeks
Post-Op Care	Apply to surgical site	TID	2 weeks
Painful Defecation	Apply 5 mins pre-bowel movement	PRN	As needed

Precautions

⚠️ Avoid if: Hypotension, heart block, or lidocaine allergy
⚠️ Discontinue if perianal rash develops
⚠️ Pregnancy Category C (limited studies)
✖️ Not for children <18 years

Disclaimer

All compounded preparations by Noor Chemist are freshly prepared upon receipt of your prescription or order to ensure maximum potency and therapeutic efficacy. Due to the meticulous quality control processes required for extemporaneous compounding, some formulations may experience a 1-day preparation delay to achieve optimal stability and performance. Product images depicting packaging and labeling are for illustrative reference only; actual containers, labels, and auxiliary materials may vary based on batch-specific pharmaceutical standards.

These formulations are designed for short-term use (typically 30-90 days), as extemporaneous compounds lack industrial preservatives. For specific storage instructions and shelf-life details pertaining to your formulation, please contact our pharmacists via our Contact Us portal.

Important Safety Notice: Skin sensitivity to active or inert ingredients may occur even with physician-recommended formulations. We strongly advise performing a patch test before full application: Apply a pea-sized amount to clean inner forearm skin, wait 24 hours, and discontinue use if redness, itching, or swelling develops. Individual reactions to ingredients like salicylic acid, essential oils, or penetration enhancers may vary. Consult your healthcare provider if you have known sensitivities.