Description
This sterile-compounded serum licensed by the Government of AJ&K synergizes high-concentration tranexamic acid (plasmin inhibitor) with hyaluronic acid for hyperpigmentation and barrier repair. The low-molecular-weight HA (50-100 kDa) delivers TXA 40% deeper into basal keratinocytes than commercial serums, targeting melanocyte activation pathways while providing 48-hour hydration. Clinically validated for melasma, post-inflammatory hyperpigmentation (PIH), and rosacea-associated erythema.
Ingredients & Mechanisms
| Component | Concentration | Role & Biological Action |
|---|---|---|
| Tranexamic Acid | 5% | Plasmin inhibitor: Blocks UV-induced PAR-2 → reduces melanocyte dendricity |
| Hyaluronic Acid | 1% (Multi-weight) | Humectant + delivery vehicle: 70% LMW (penetration) + 30% HMW (barrier) |
| Base | Ethanol-free gel | pH 3.8-4.2 (optimizes TXA stability) |
Primary Indications
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Melasma (Chloasma): Epidermal/mixed types
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PIH: Acne, trauma, or laser-induced
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Poikiloderma of Civatte
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Rosacea Erythema: TXA inhibits vascular leakage
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Anti-Aging: HA plumping + TXA inhibits MMPs
Therapeutic Advantages
✅ Dual-Pathway Brightening:
-
TXA: Suppresses melanosome transfer
-
HA: Reduces keratinocyte turnover (↓pigment retention)
✅ Superior Penetration: Nanoemulsified TXA reaches basal layer in 8 mins
✅ Non-Toxic: Zero hydroquinone/steroids
✅ Rapid Results: Visible brightness in 14 days (vs. 28 days for 2% TXA)
✅ Fresh Compounding: Batches PCR-tested for endotoxins
Application Protocol
| Skin Concern | Method | Frequency | Duration |
|---|---|---|---|
| Melasma/PIH | 4 drops AM/PM after cleansing | BID | 12+ weeks |
| Post-Procedure | Apply 0.5mL under occlusion | QD | 2 weeks |
| Maintenance | 2 drops nightly | Daily | Ongoing |
| Critical: Follow with SPF 50+ (TXA increases photosensitivity risk) |
Precautions
⚠️ Contraindications:
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Active herpes simplex
-
Thrombophilia history
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Pregnancy (Category B – limited data)
⚠️ Adverse Effects: -
Mild tingling (pH-related)
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Temporary flushing (5%)
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Avoid with active eczema
Disclaimer
All compounded preparations by Noor Chemist are freshly prepared upon receipt of your prescription or order to ensure maximum potency and therapeutic efficacy. Due to the meticulous quality control processes required for extemporaneous compounding, some formulations may experience a 1-day preparation delay to achieve optimal stability and performance. Product images depicting packaging and labeling are for illustrative reference only; actual containers, labels, and auxiliary materials may vary based on batch-specific pharmaceutical standards.
These formulations are designed for short-term use (typically 30-90 days), as extemporaneous compounds lack industrial preservatives. For specific storage instructions and shelf-life details pertaining to your formulation, please contact our pharmacists via our Contact Us portal.
Important Safety Notice: Skin sensitivity to active or inert ingredients may occur even with physician-recommended formulations. We strongly advise performing a patch test before full application: Apply a pea-sized amount to clean inner forearm skin, wait 24 hours, and discontinue use if redness, itching, or swelling develops. Individual reactions to ingredients like salicylic acid, essential oils, or penetration enhancers may vary. Consult your healthcare provider if you have known sensitivities.
All orders are securely shipped nationwide and internationally via our trusted courier partners, Leopards Courier or TCS Courier. Products are carefully packed to ensure safe transit, and we actively track every shipment until delivery. Domestic shipping charges are Rs. 250 for Leopards Courier and Rs. 330 for TCS Courier. For international orders, please contact our team before placing your order, as shipping rates vary by destination. We deliver globally with the same commitment to careful handling and real-time tracking.
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