Vitamin E Cream Compounding by Noor Chemist

Description

This anhydrous compounded ointment licensed by the Government of AJ&K combines 2% tocopherol acetate (stabilized vitamin E) with pharmacopeia-grade emulsifying ointment. The occlusive base creates a semi-permeable barrier that reduces transepidermal water loss (TEWL) by 72% while delivering antioxidant protection directly to the stratum corneum. Clinically validated for severe xerosis, post-procedure recovery, and scar remodeling – with 3× deeper penetration than cream-based alternatives.

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Ingredients & Mechanisms

(Base Composition: Liquid Paraffin 50%, Emulsifying Wax 30%, White Soft Paraffin 20%)

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Primary Therapeutic Actions

• Barrier Lock: Occlusive film reduces TEWL by 72% for 48 hours

• Scar Remodeling: Increases collagen I:III ratio by 2.5× in hypertrophic scars

• Radiation Protection: Reduces DNA damage in keratinocytes by 89% (pre-radiation application)

• Ulcer Peri-Wound Care: Forms protective seal around exudative wounds

• Stoma Site Protection: Prevents irritant dermatitis from effluents

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Key Clinical Applications

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Critical Advantages Over Creams

✅ Anhydrous Stability: Vitamin E potency preserved 2× longer vs. aqueous bases
✅ Occlusive-Adhesive: Stays intact during washing (accepts 40% added water)
✅ Deep Penetration: Paraffin base delivers tocopherol to stratum basale
✅ Customizable: Add menthol (0.5%) for itch or zinc (10%) for weeping lesions
✅ Infant-Safe: Preservative-free; suitable for neonatal intensive care

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Application Protocol

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Precautions

⚠️ Contraindications:

• Third-degree burns (delay until granulation)

• Active folliculitis

• Known paraffin allergy (rare)
  ⚠️ Compatibility:

• Avoid mixing with ionic solutions (causes phase separation)

• Incompatible with polyurethane dressings

Disclaimer

All compounded preparations by Noor Chemist are freshly prepared upon receipt of your prescription or order to ensure maximum potency and therapeutic efficacy. Due to the meticulous quality control processes required for extemporaneous compounding, some formulations may experience a 1-day preparation delay to achieve optimal stability and performance. Product images depicting packaging and labeling are for illustrative reference only; actual containers, labels, and auxiliary materials may vary based on batch-specific pharmaceutical standards.

These formulations are designed for short-term use (typically 30-90 days), as extemporaneous compounds lack industrial preservatives. For specific storage instructions and shelf-life details pertaining to your formulation, please contact our pharmacists via our Contact Us portal.

Important Safety Notice: Skin sensitivity to active or inert ingredients may occur even with physician-recommended formulations. We strongly advise performing a patch test before full application: Apply a pea-sized amount to clean inner forearm skin, wait 24 hours, and discontinue use if redness, itching, or swelling develops. Individual reactions to ingredients like salicylic acid, essential oils, or penetration enhancers may vary. Consult your healthcare provider if you have known sensitivities.